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The oligomeric state of CtBP determines its role as a transcriptional co-activator and co-repressor of Wingless targets
C-terminal-binding protein (CtBP) is a well-characterized transcriptional co-repressor that requires homo-dimerization for its activity. CtBP can both repress and activate Wingless nuclear targets in Drosophila. Here, we examine the role of CtBP dimerization in these opposing processes. CtBP mutants...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098475/ https://ncbi.nlm.nih.gov/pubmed/21468031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.100 |
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