Cargando...
Anoikis, initiated by Mcl-1 degradation and Bim induction, is deregulated during oncogenesis
Anoikis, a Bax dependent apoptosis triggered by detachment from the extracellular matrix, is often dysfunctional in metastatic cancer cells. Using wild type and c-Src transformed NIH3T3 cells as a model we identified Mcl-1 degradation and Bim upregulation as a critical determinant of anoikis initiat...
Gardado en:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2258556/ https://ncbi.nlm.nih.gov/pubmed/18006817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-3148 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|