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Hsp110 Chaperones Regulate Prion Formation and Propagation in S. cerevisiae by Two Discrete Activities

The cytosolic chaperone network of Saccharomyces cerevisiae is intimately associated with the emergence and maintenance of prion traits. Recently, the Hsp110 protein, Sse1, has been identified as a nucleotide exchange factor (NEF) for both cytosolic Hsp70 chaperone family members, Ssa1 and Ssb1. We...

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Autors principals: Sadlish, Heather, Rampelt, Heike, Shorter, James, Wegrzyn, Renee D., Andréasson, Claes, Lindquist, Susan, Bukau, Bernd
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258148/
https://ncbi.nlm.nih.gov/pubmed/18335038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001763
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