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Mutations in the Hydrophobic Core of Ubiquitin Differentially Affect its Recognition by Receptor Proteins

Ubiquitin is one of the most highly conserved signaling proteins in eukaryotes. In carrying out its myriad functions, ubiquitin conjugated to substrate proteins interacts with dozens of different receptor proteins that link the ubiquitin signal to various biological outcomes. Here, we report mutatio...

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Detalhes bibliográficos
Main Authors: Haririnia, Aydin, Verma, Rati, Purohit, Nisha, Twarog, Michael Z., Deshaies, Raymond J., Bolon, Dan, Fushman, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254529/
https://ncbi.nlm.nih.gov/pubmed/18054791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.11.016
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