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Helix periodicity, topology, and dynamics of membrane-associated α-Synuclein

The protein α-Synuclein (aS) is a synaptic vesicle-associated regulator of synaptic strength and dopamine homeostasis with a pathological role in Parkinson’s disease. The normal function of aS depends on a membrane-associated conformation that is adopted upon binding to negatively charged lipid surf...

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Detalhes bibliográficos
Main Authors: Bussell, Robert, Ramlall, Trudy Fiona, Eliezer, David
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253433/
https://ncbi.nlm.nih.gov/pubmed/15741347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041255905
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