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Structure and dynamics of the extended‐helix state of alpha‐synuclein: Intrinsic lability of the linker region
The Parkinson's protein alpha‐synuclein binds to synaptic vesicles in vivo and adopts a highly extended helical conformation when binding to lipid vesicles in vitro. High‐resolution structural analysis of alpha‐synuclein bound to small lipid or detergent micelles revealed two helices connected...
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| Publicado no: | Protein Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6032355/ https://ncbi.nlm.nih.gov/pubmed/29663556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3426 |
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