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Prediction of aggregation rate and aggregation-prone segments in polypeptide sequences
The reliable identification of β-aggregating stretches in protein sequences is essential for the development of therapeutic agents for Alzheimer’s and Parkinson’s diseases, as well as other pathological conditions associated with protein deposition. Here, a model based on physicochemical properties...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253302/ https://ncbi.nlm.nih.gov/pubmed/16195556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051471205 |
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