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Aβ42 Mutants with Different Aggregation Profiles Induce Distinct Pathologies in Drosophila
Aggregation of the amyloid-β-42 (Aβ42) peptide in the brain parenchyma is a pathological hallmark of Alzheimer's disease (AD), and the prevention of Aβ aggregation has been proposed as a therapeutic intervention in AD. However, recent reports indicate that Aβ can form several different prefibri...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2250771/ https://ncbi.nlm.nih.gov/pubmed/18301778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001703 |
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