Herpes Simplex Virus Type 1 DNA Is Immunostimulatory In Vitro and In Vivo
Recently, prokaryotic DNAs containing unmethylated CpG motifs have been shown to be intrinsically immunostimulatory both in vitro and in vivo, tending to promote Th1-like responses. In contrast, CpG dinucleotides in mammalian DNAs are extensively methylated on cytosines and hence immunologically ine...
Zapisane w:
| Wydane w: | J Virol |
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| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology (ASM)
2003
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC225007/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14512563/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.20.11158-11169.2003 |
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