Herpes Simplex Virus Type 1 DNA Is Immunostimulatory In Vitro and In Vivo

Recently, prokaryotic DNAs containing unmethylated CpG motifs have been shown to be intrinsically immunostimulatory both in vitro and in vivo, tending to promote Th1-like responses. In contrast, CpG dinucleotides in mammalian DNAs are extensively methylated on cytosines and hence immunologically ine...

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Dades bibliogràfiques

Publicat a:	J Virol
Autors principals:	Lundberg, Patric, Welander, Paula, Han, Xiao, Cantin, Edouard
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2003
Matèries:	Pathogenesis and Immunity
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC225007/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14512563/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.20.11158-11169.2003
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