Herpes Simplex Virus Type 1 DNA Is Immunostimulatory In Vitro and In Vivo

Recently, prokaryotic DNAs containing unmethylated CpG motifs have been shown to be intrinsically immunostimulatory both in vitro and in vivo, tending to promote Th1-like responses. In contrast, CpG dinucleotides in mammalian DNAs are extensively methylated on cytosines and hence immunologically ine...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	J Virol
Prif Awduron:	Lundberg, Patric, Welander, Paula, Han, Xiao, Cantin, Edouard
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 2003
Pynciau:	Pathogenesis and Immunity
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC225007/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14512563/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.20.11158-11169.2003
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!