Herpes Simplex Virus Type 1 DNA Is Immunostimulatory In Vitro and In Vivo

Recently, prokaryotic DNAs containing unmethylated CpG motifs have been shown to be intrinsically immunostimulatory both in vitro and in vivo, tending to promote Th1-like responses. In contrast, CpG dinucleotides in mammalian DNAs are extensively methylated on cytosines and hence immunologically ine...

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Podrobná bibliografie

Vydáno v:	J Virol
Hlavní autoři:	Lundberg, Patric, Welander, Paula, Han, Xiao, Cantin, Edouard
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Pathogenesis and Immunity
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC225007/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14512563/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.20.11158-11169.2003
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