Bcl-X(L) interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

Recent studies indicate that Caenorhabditis elegans CED-4 interacts with and promotes the activation of the death protease CED-3, and that this activation is inhibited by CED-9. Here we show that a mammalian homolog of CED-4, Apaf-1, can associate with several death proteases, including caspase-4, c...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Hu, Yuanming, Benedict, Mary A., Wu, Dayang, Inohara, Naohiro, Núñez, Gabriel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22498/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9539746/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.8.4386
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