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Bcl-X(L) interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

Recent studies indicate that Caenorhabditis elegans CED-4 interacts with and promotes the activation of the death protease CED-3, and that this activation is inhibited by CED-9. Here we show that a mammalian homolog of CED-4, Apaf-1, can associate with several death proteases, including caspase-4, c...

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Bibliografiske detaljer
Main Authors: Hu, Yuanming, Benedict, Mary A., Wu, Dayang, Inohara, Naohiro, Núñez, Gabriel
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22498/
https://ncbi.nlm.nih.gov/pubmed/9539746
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