Cytochrome c binding to Apaf-1: The effects of dATP and ionic strength
In the apoptosis pathway in mammals, cytochrome c and dATP are critical cofactors in the activation of caspase 9 by Apaf-1. Until now, the detailed sequence of events in which these cofactors interact has been unclear. Here, we show through fluorescence polarization experiments that cytochrome c can...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17271/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11035811/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.220416197 |
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