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Single Strand Binding Proteins Increase the Processivity of DNA Unwinding by the Hepatitis C Virus Helicase
The nonstructural NS3 protein of the Hepatitis C virus (HCV) is a multi-functional enzyme with an N-terminal serine-protease activity and a C-terminal helicase activity. The helicase is capable of unwinding both DNA and RNA duplexes; however, the overall processivity of the helicase is fairly low. W...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2249756/ https://ncbi.nlm.nih.gov/pubmed/18155046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.10.070 |
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