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An intramolecular FRET system monitors fingers subdomain opening in Klentaq1
A major goal of polymerase research is to determine the mechanism through which a nucleotide complementary to a templating DNA base is selected and delivered to the polymerase active site. Structural evidence suggests a large open-to-closed conformational change affecting the fingers subdomain as be...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2248307/ https://ncbi.nlm.nih.gov/pubmed/18287276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073309208 |
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