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An intramolecular FRET system monitors fingers subdomain opening in Klentaq1

A major goal of polymerase research is to determine the mechanism through which a nucleotide complementary to a templating DNA base is selected and delivered to the polymerase active site. Structural evidence suggests a large open-to-closed conformational change affecting the fingers subdomain as be...

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Hlavní autoři: Allen, William J., Rothwell, Paul J., Waksman, Gabriel
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248307/
https://ncbi.nlm.nih.gov/pubmed/18287276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073309208
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