Loading...

dNTP-dependent Conformational Transitions in the Fingers Subdomain of Klentaq1 DNA Polymerase: INSIGHTS INTO THE ROLE OF THE “NUCLEOTIDE-BINDING” STATE

DNA polymerases are responsible for the accurate replication of DNA. Kinetic, single-molecule, and x-ray studies show that multiple conformational states are important for DNA polymerase fidelity. Using high precision FRET measurements, we show that Klentaq1 (the Klenow fragment of Thermus aquaticus...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Rothwell, Paul J., Allen, William J., Sisamakis, Evangelos, Kalinin, Stanislav, Felekyan, Suren, Widengren, Jerker, Waksman, Gabriel, Seidel, Claus A. M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650393/
https://ncbi.nlm.nih.gov/pubmed/23525110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.432690
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!