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Calpain and proteasomal regulation of antiretroviral zinc finger protein OTK18 in human macrophages: Visualization in live cells by intramolecular FRET

As part of the innate immune defense against HIV infection, OTK18, a zinc finger protein, is upregulated in human macrophages and reduces viral replication through suppression of viral long-terminal repeat promoter activity. Although we know that the processing products of OTK18 accumulate in the cy...

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Detalhes bibliográficos
Main Authors: Martinez, Lindsey B., Walsh, Shannon M., Jacobsen, Michael T., Sato, Shinji, Wiederin, Jayme, Ciborowski, Pawel, Ikezu, Tsuneya
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644346/
https://ncbi.nlm.nih.gov/pubmed/19034669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-008-9140-4
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