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The C terminus of β-tubulin regulates vinblastine-induced tubulin polymerization

Oligoanions such as sodium triphosphate or GTP prevent and/or reverse vinblastine-induced polymerization of tubulin. We now show that the anions of glutamate-rich extreme C termini of tubulin are similarly involved in the regulation of the vinblastine effect. Cleavage of the C termini by limited pro...

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Bibliografske podrobnosti
Main Authors: Rai, Sadananda S., Wolff, J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC22475/
https://ncbi.nlm.nih.gov/pubmed/9539723
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