The C terminus of β-tubulin regulates vinblastine-induced tubulin polymerization
Oligoanions such as sodium triphosphate or GTP prevent and/or reverse vinblastine-induced polymerization of tubulin. We now show that the anions of glutamate-rich extreme C termini of tubulin are similarly involved in the regulation of the vinblastine effect. Cleavage of the C termini by limited pro...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1998
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22475/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9539723/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.8.4253 |
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