A tumour spheroid model for antibody-targeted therapy of micrometastases.

Human neuroblastoma cells grown as tumour spheroids were briefly incubated with a conjugate of 131I and an anti-human neuroectodermal monoclonal antibody UJ13A. Unbound 131I was removed by washing and the spheroids observed in culture conditions for up to 4 weeks. Spheroid response to irradiation wa...

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Main Authors: Walker, K. A., Murray, T., Hilditch, T. E., Wheldon, T. E., Gregor, A., Hann, I. M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1988
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246487/
https://ncbi.nlm.nih.gov/pubmed/3166889
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