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Modelling Acidosis and the Cell Cycle in Multicellular Tumour Spheroids
A partial differential equation model is developed to understand the effect that nutrient and acidosis have on the distribution of proliferating and quiescent cells within a multicellular tumour spheroid. The rates of cell quiescence and necrosis are assumed to depend upon the local nutrient and aci...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4010153/ https://ncbi.nlm.nih.gov/pubmed/22155133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2011.11.009 |
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