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The effect of adriamycin and 4'-deoxydoxorubicin on cell survival of human lung tumour cells grown in monolayer and as spheroids.

Using growth delay and clonogenic cell survival as end points, we have shown that the 3-dimensional structure of human lung tumour spheroids confers a degree of resistance to the anthracyclines adriamycin and 4'-deoxydoxorubicin, relative to cells grown as monolayer. 4'-deoxydoxorubicin in...

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Bibliografski detalji
Glavni autori: Kerr, D. J., Wheldon, T. E., Kerr, A. M., Freshney, R. I., Kaye, S. B.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1986
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001622/
https://ncbi.nlm.nih.gov/pubmed/3756078
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