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De Novo Asymmetric Syntheses of d-, l- and 8-epi-Swainsonine

A highly enantioselective and stereocontrolled approach to d-, l- and 8-epi-d-swainsonine has been developed from achiral furan and γ-butyrolactone. A one-pot hydrogenolysis of both azide and benzyl ether followed by an intramolecular reductive amination has been employed as key step to establish th...

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Detalhes bibliográficos
Main Authors: Guo, Haibing, O’Doherty, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2245874/
https://ncbi.nlm.nih.gov/pubmed/18283329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2007.10.109
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