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Role of DNA Methyltransferases in Regulation of Human Ribosomal RNA Gene Transcription

We have previously demonstrated that the expression of human ribosomal RNA genes (rDNA) in normal and cancer cells is differentially regulated by methylation of the promoter CpG islands. Furthermore, we showed that the methyl CpG-binding protein MBD2 plays a selective role in the methylation-mediate...

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Autores principales: Majumder, Sarmila, Ghoshal, Kalpana, Datta, Jharna, Smith, David Spencer, Bai, Shoumei, Jacob, Samson T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2243234/
https://ncbi.nlm.nih.gov/pubmed/16735507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M601155200
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