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Complexes of the enzyme phosphomannomutase/phosphoglucomutase with a slow substrate and an inhibitor

Two complexes of the enzyme phosphomannomutase/phosphoglucomutase (PMM/PGM) from Pseudomonas aeruginosa with a slow substrate and with an inhibitor have been characterized by X-ray crystallography. Both ligands induce an interdomain rearrangement in the enzyme that creates a highly buried active sit...

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Detalhes bibliográficos
Main Authors: Regni, Catherine, Shackelford, Grant S., Beamer, Lesa J.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242917/
https://ncbi.nlm.nih.gov/pubmed/16880541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106025887
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