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Prediction of three-dimensional structures of enzyme-substrate and enzyme-inhibitor complexes of lysozyme.

Conformational energy calculations were used to predict the three-dimensional structures of enzyme-substrate and enzyme-inhibitor complexes of lysozyme. A global search method, involving the use of a disaccharide fragment molecule, was used initially to determine all favorable binding regions at the...

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Detalhes bibliográficos
Main Authors: Pincus, M R, Zimmerman, S S, Scheraga, H A
Formato: Artigo
Idioma:Inglês
Publicado em: 1976
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC431428/
https://ncbi.nlm.nih.gov/pubmed/1069981
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