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Substrate Binding and Formation of an Occluded State in the Leucine Transporter()

Translocation through the extracellular vestibule and binding of leucine in the leucine transporter (LeuT) have been studied with molecular dynamics simulations. More than 0.1 μs of all-atom molecular dynamics simulations have been performed on different combinations of LeuT, bound substrate, and bo...

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Detalhes bibliográficos
Main Authors: Celik, Leyla, Schiøtt, Birgit, Tajkhorshid, Emad
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242742/
https://ncbi.nlm.nih.gov/pubmed/18024499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.117580
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