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Ion-Releasing State of a Secondary Membrane Transporter
The crystal structure of Na(+)-coupled galactose symporter (vSGLT) reports the transporter in its substrate-bound state, with a Na(+) ion modeled in a binding site corresponding to that of a homologous protein, leucine transporter (LeuT). In repeated molecular dynamics simulations, however, we find...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Biophysical Society
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784569/ https://ncbi.nlm.nih.gov/pubmed/19948113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.005 |
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