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Transient formation of water-conducting states in membrane transporters

Membrane transporters rely on highly coordinated structural transitions between major conformational states for their function, to prevent simultaneous access of the substrate binding site to both sides of the membrane—a mode of operation known as the alternating access model. Although this mechanis...

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Detalhes bibliográficos
Main Authors: Li, Jing, Shaikh, Saher A., Enkavi, Giray, Wen, Po-Chao, Huang, Zhijian, Tajkhorshid, Emad
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651479/
https://ncbi.nlm.nih.gov/pubmed/23610412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218986110
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