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Transient formation of water-conducting states in membrane transporters
Membrane transporters rely on highly coordinated structural transitions between major conformational states for their function, to prevent simultaneous access of the substrate binding site to both sides of the membrane—a mode of operation known as the alternating access model. Although this mechanis...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3651479/ https://ncbi.nlm.nih.gov/pubmed/23610412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218986110 |
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