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The allosteric transition in DnaK probed by infrared difference spectroscopy. Concerted ATP-induced rearrangement of the substrate binding domain

The biological activity of DnaK, the bacterial representative of the Hsp70 protein family, is regulated by the allosteric interaction between its nucleotide and peptide substrate binding domains. Despite the importance of the nucleotide-induced cycling of DnaK between substrate-accepting and releasi...

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Main Authors: Moro, Fernando, Fernández-Sáiz, Vanesa, Muga, Arturo
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242457/
https://ncbi.nlm.nih.gov/pubmed/16384998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051732706
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