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Sumoylation regulates multiple aspects of mammalian poly(A) polymerase function
The addition of the poly(A) tail to the ends of eukaryotic mRNAs is catalyzed by poly(A) polymerase (PAP). PAP activity is known to be highly regulated, for example, by alternative splicing and phosphorylation. In this study we show that the small ubiquitin-like modifier (SUMO) plays multiple roles...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2238671/ https://ncbi.nlm.nih.gov/pubmed/18281463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1628208 |
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