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Sumoylation regulates multiple aspects of mammalian poly(A) polymerase function

The addition of the poly(A) tail to the ends of eukaryotic mRNAs is catalyzed by poly(A) polymerase (PAP). PAP activity is known to be highly regulated, for example, by alternative splicing and phosphorylation. In this study we show that the small ubiquitin-like modifier (SUMO) plays multiple roles...

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Detalhes bibliográficos
Main Authors: Vethantham, Vasupradha, Rao, Nishta, Manley, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238671/
https://ncbi.nlm.nih.gov/pubmed/18281463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1628208
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