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Sumoylation regulates multiple aspects of mammalian poly(A) polymerase function

The addition of the poly(A) tail to the ends of eukaryotic mRNAs is catalyzed by poly(A) polymerase (PAP). PAP activity is known to be highly regulated, for example, by alternative splicing and phosphorylation. In this study we show that the small ubiquitin-like modifier (SUMO) plays multiple roles...

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書目詳細資料
Main Authors: Vethantham, Vasupradha, Rao, Nishta, Manley, James L.
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238671/
https://ncbi.nlm.nih.gov/pubmed/18281463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1628208
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