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Morphogenetic movements at gastrulation require the SH2 tyrosine phosphatase Shp2

The SH2 domain-containing tyrosine phosphatase Shp2 plays a pivotal role during the gastrulation of vertebrate embryos. However, because of the complex phenotype observed in mouse mutant embryos, the precise role of Shp2 during development is unclear. To define the specific functions of this phospha...

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Bibliographic Details
Main Authors: Saxton, Tracy M., Pawson, Tony
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC22373/
https://ncbi.nlm.nih.gov/pubmed/10097116
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