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NEGATIVE COOPERATIVITY IN REGULATORY ENZYMES

Negative cooperativity has been observed in CTP synthetase, an allosteric enzyme which contains a regulatory site. Thus, the same enzyme exhibits negative cooperativity for GTP (an effector) and glutamine (a substrate) and positive cooperativity for ATP and UTP (both substrates). In the process of t...

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Detalhes bibliográficos
Main Authors: Levitzki, Alexander, Koshland, D. E.
Formato: Artigo
Idioma:Inglês
Publicado em: 1969
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC223623/
https://ncbi.nlm.nih.gov/pubmed/5256410
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