NEGATIVE COOPERATIVITY IN REGULATORY ENZYMES
Negative cooperativity has been observed in CTP synthetase, an allosteric enzyme which contains a regulatory site. Thus, the same enzyme exhibits negative cooperativity for GTP (an effector) and glutamine (a substrate) and positive cooperativity for ATP and UTP (both substrates). In the process of t...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1969
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC223623/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5256410/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.62.4.1121 |
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