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NEGATIVE COOPERATIVITY IN REGULATORY ENZYMES

Negative cooperativity has been observed in CTP synthetase, an allosteric enzyme which contains a regulatory site. Thus, the same enzyme exhibits negative cooperativity for GTP (an effector) and glutamine (a substrate) and positive cooperativity for ATP and UTP (both substrates). In the process of t...

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Autors principals: Levitzki, Alexander, Koshland, D. E.
Format: Artigo
Idioma:Inglês
Publicat: 1969
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC223623/
https://ncbi.nlm.nih.gov/pubmed/5256410
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