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Accelerated atherogenesis and neointima formation in heparin cofactor II–deficient mice

Heparin cofactor II (HCII) is a plasma protein that inhibits thrombin when bound to dermatan sulfate or heparin. HCII-deficient mice are viable and fertile but rapidly develop thrombosis of the carotid artery after endothelial injury. We now report the effects of HCII deficiency on atherogenesis and...

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Detalhes bibliográficos
Main Authors: Vicente, Cristina P., He, Li, Tollefsen, Douglas M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234791/
https://ncbi.nlm.nih.gov/pubmed/17878401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-04-086611
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