Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis

Autophagy is triggered in vascular smooth muscle cells (VSMCs) of diseased arterial vessels. However, the role of VSMC autophagy in cardiovascular disease is poorly understood. Therefore, we investigated the effect of defective autophagy on VSMC survival and phenotype and its significance in the dev...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Grootaert, Mandy OJ, da Costa Martins, Paula A, Bitsch, Nicole, Pintelon, Isabel, De Meyer, Guido RY, Martinet, Wim, Schrijvers, Dorien M
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Basic Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824610/
https://ncbi.nlm.nih.gov/pubmed/26391655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1096485
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