Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis

Autophagy is triggered in vascular smooth muscle cells (VSMCs) of diseased arterial vessels. However, the role of VSMC autophagy in cardiovascular disease is poorly understood. Therefore, we investigated the effect of defective autophagy on VSMC survival and phenotype and its significance in the dev...

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Publicado en:Autophagy
Autores principales: Grootaert, Mandy OJ, da Costa Martins, Paula A, Bitsch, Nicole, Pintelon, Isabel, De Meyer, Guido RY, Martinet, Wim, Schrijvers, Dorien M
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
Materias:
Basic Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824610/
https://ncbi.nlm.nih.gov/pubmed/26391655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1096485
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