Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis

Autophagy is triggered in vascular smooth muscle cells (VSMCs) of diseased arterial vessels. However, the role of VSMC autophagy in cardiovascular disease is poorly understood. Therefore, we investigated the effect of defective autophagy on VSMC survival and phenotype and its significance in the dev...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Autophagy
Prif Awduron: Grootaert, Mandy OJ, da Costa Martins, Paula A, Bitsch, Nicole, Pintelon, Isabel, De Meyer, Guido RY, Martinet, Wim, Schrijvers, Dorien M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2015
Pynciau:
Basic Research Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824610/
https://ncbi.nlm.nih.gov/pubmed/26391655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1096485
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