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Vascular dermatan sulfate regulates the antithrombotic activity of heparin cofactor II
Heparin cofactor II (HCII)–deficient mice form occlusive thrombi more rapidly than do wild-type mice following injury to the carotid arterial endothelium. Dermatan sulfate (DS) and heparan sulfate (HS) increase the rate of inhibition of thrombin by HCII in vitro, but it is unknown whether vascular g...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2288722/ https://ncbi.nlm.nih.gov/pubmed/18281504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-12-127928 |
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