טוען...
MISMATCH REPAIR-DEPENDENT ITERATIVE EXCISION AT IRREPARABLE O(6)-METHYLGUANINE LESIONS IN HUMAN NUCLEAR EXTRACTS
The response of mammalian cells to S(N)1 DNA methylators depends on functional MutSα and MutLα. Cells deficient in either of these activities are resistant to the cytotoxic effects of this class of chemotherapeutic drug. Because killing by S(N)1 methylators has been attributed to O(6)-methylguanine...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2006
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234603/ https://ncbi.nlm.nih.gov/pubmed/16772289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M603667200 |
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