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Regulation of KCNQ2/KCNQ3 Current by G Protein Cycling: The Kinetics of Receptor-mediated Signaling by G(q)

Receptor-mediated modulation of KCNQ channels regulates neuronal excitability. This study concerns the kinetics and mechanism of M(1) muscarinic receptor–mediated regulation of the cloned neuronal M channel, KCNQ2/KCNQ3 (Kv7.2/Kv7.3). Receptors, channels, various mutated G-protein subunits, and an o...

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Main Authors: Suh, Byung-Chang, Horowitz, Lisa F., Hirdes, Wiebke, Mackie, Ken, Hille, Bertil
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234571/
https://ncbi.nlm.nih.gov/pubmed/15173220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200409029
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