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Phospholipase C in Living Cells: Activation, Inhibition, Ca(2+) Requirement, and Regulation of M Current
We have further tested the hypothesis that receptor-mediated modulation of KCNQ channels involves depletion of phosphatidylinositol 4,5-bisphosphate (PIP(2)) by phosphoinositide-specific phospholipase C (PLC). We used four parallel assays to characterize the agonist-induced PLC response of cells (ts...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2266577/ https://ncbi.nlm.nih.gov/pubmed/16129772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509309 |
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