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Impaired vascular mechanotransduction in a transgenic mouse model of CADASIL arteriopathy
BACKGROUND AND PURPOSE: CADASIL is an inherited small-vessel disease responsible for lacunar strokes and cognitive impairment. The disease is caused by highly stereotyped mutations in Notch3, expression of which is highly restricted to vascular smooth muscle cells (vSMC). The underlying vasculopathy...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Lippincott Williams & Wilkins
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234452/ https://ncbi.nlm.nih.gov/pubmed/15569862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.STR.0000149949.92854.45 |
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