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Transgenic Mice Expressing Mutant Notch3 Develop Vascular Alterations Characteristic of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an increasingly recognized adult-onset autosomal dominant vascular dementia, caused by highly stereotyped mutations in the Notch3 receptor. CADASIL is a widespread angiopathy characterized by a de...

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Main Authors: Ruchoux, Marie Magdeleine, Domenga, Valérie, Brulin, Peggy, Maciazek, Jacqueline, Limol, Sylvie, Tournier-Lasserve, Elisabeth, Joutel, Anne
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851116/
https://ncbi.nlm.nih.gov/pubmed/12507916
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