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MerTK is required for apoptotic cell–induced T cell tolerance

Self-antigens expressed by apoptotic cells (ACs) may become targets for autoimmunity. Tolerance to these antigens is partly established by an ill-defined capacity of ACs to inhibit antigen-presenting cells such as dendritic cells (DCs). We present evidence that the receptor tyrosine kinase Mer (MerT...

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Hlavní autoři: Wallet, Mark A., Sen, Pradip, Flores, Rafael R., Wang, Yaming, Yi, Zuoan, Huang, Yingsu, Mathews, Clayton E., Earp, H. Shelton, Matsushima, Glenn, Wang, Bo, Tisch, Roland
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234377/
https://ncbi.nlm.nih.gov/pubmed/18195070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062293
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