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Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors

Many vaccination strategies and immune cell therapies aim at increasing the numbers of memory T cells reactive to protective antigens. However, the differentiation lineage and therefore the optimal generation conditions of CD4 memory cells remain controversial. Linear and divergent differentiation m...

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Autors principals: Löhning, Max, Hegazy, Ahmed N., Pinschewer, Daniel D., Busse, Dorothea, Lang, Karl S., Höfer, Thomas, Radbruch, Andreas, Zinkernagel, Rolf M., Hengartner, Hans
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234365/
https://ncbi.nlm.nih.gov/pubmed/18195073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071855
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